Phenotypic and genotypic profile of pyrethroid resistance in populations of the mosquito Aedes aegypti from Goiânia, Central West Brazil.

نویسندگان

  • Francesca Guaracyaba Garcia Chapadense
  • Everton Kort Kamp Fernandes
  • José Bento Pereira Lima
  • Ademir Jesus Martins
  • Luana Carrara Silva
  • Welington Tristão da Rocha
  • Adelair Helena Dos Santos
  • Pedro Cravo
چکیده

INTRODUCTION The mosquito Aedes aegypti has evolved resistance to pyrethroid insecticides. The present study evaluated Ae. aegypti from Goiânia for the resistant phenotype and for mutations associated with resistance. METHODS Insecticide dose-response bioassays were conducted on mosquitoes descended from field-collected eggs, and polymerase chain reaction (PCR) was used to genotype 90 individuals at sites implicated in pyrethroid resistance. RESULTS All mosquito populations displayed high levels of resistance to deltamethrin, as well as high frequencies of the 1016Ile kdr and 1534Cys kdrmutations. CONCLUSIONS Aedes aegypti populations in the Goiânia area are highly resistant to deltamethrin, presumably due to high frequencies of kdr(knockdown-resistance) mutations.

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عنوان ژورنال:
  • Revista da Sociedade Brasileira de Medicina Tropical

دوره 48 5  شماره 

صفحات  -

تاریخ انتشار 2015